My Dog is acting "WEIRD" .... Advice PLEASE !!!!?

One of my dogs Shiloh our beagle has been acting strange lately. Weve had her for 5 years and she has always been a well behaved do except for the barking and chasing people alongside the fence outside. Now she has begun chewing and ripping up clothing,shoes,paper towels .... Mostly at night. There have been NO Changes in the home whatsoever. Her last vet check about 3 months ago showed her to be in great health. We havent changed her food,routine or anything. Also last week she peed on my bedroom floor for no reason ... She is completly housebroken and in my opinion she seemed to do it on spite for some unknown reason. She has begun acting "Weird" for about 2 weeks. Any Ideas as to what could be going on ?? I love her Soo much and Im concerned. Thank you